E
Tier
IGF-1 splice variant driving muscle repair.
Muscle & Performance
Protein, splice variant of IGF-1
WADA Status:
Prohibited at all times (S2.3)
Human Trial Scoreboard
Completed human RCTs
None completed
Largest Human Study
No human studies
Longest exposure
None studied
Most Recent Trial
No completed trial
Description
Mechano growth factor is a naturally occurring variant of IGF-1 produced by muscle tissue in response to mechanical loading, which is to say in response to exercise. It appears to help activate satellite cells, the reserve cells that contribute to muscle repair and growth. That is real physiology and it is a legitimate area of muscle research. The leap made in marketing is the familiar one: observing that your body produces a molecule when you train is not evidence that injecting it produces the same result. No human trial has administered it. It has never been developed as a medicine, and it is prohibited in tested sport.
What Are The Claims
Claims made for this compound: Muscle repair; Satellite-cell activation
Evidence
An IGF-1 splice variant studied in muscle biology. Human evidence for the marketed use does not exist.
Evidence Strength
Animal/preclinical only
Caveats
Safety
Alternative Measures
Legal Status
US
Not approved
UK
Not approved
EU
Not approved
AU
Not approved
WADA
Prohibited at all times (S2.3)
Not approved. Research chemical. WADA-prohibited.
Citations
No completed peer-reviewed human clinical trial exists for this compound. Where a citation is absent below, that absence is the finding.