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Tier

LL-37 (Cathelicidin)

LL-37 (Cathelicidin)

LL-37 (Cathelicidin)

Antimicrobial host-defense peptide studied for infection and wound healing.

Immune Support

Peptide, 37 amino acids

WADA Status:

Not listed

Human Trial Scoreboard

Completed human RCTs

0
0
0

None completed

Largest Human Study

0
0
0

Small academic studies

Longest exposure

0
0
0

Duration not verified

Most Recent Trial

0
0
0

Year not verified

Description

LL-37 is a thirty seven amino acid antimicrobial peptide that your own body produces, the active fragment of a protein called cathelicidin. It is part of innate immunity, the fast general-purpose defence system that acts before the more targeted immune response engages, and it can disrupt bacterial membranes directly as well as signalling to other immune cells. It is genuinely important biology and an active research area, particularly given concerns about antibiotic resistance. It is not an approved treatment. Human studies are small and academic, no completed randomised controlled trial establishes it as a therapy, and treating an endogenous immune peptide as a substitute for an antibiotic is not supported by anything published.

What Are The Claims

Claims made for this compound: Antimicrobial; Supports wound healing; Immune modulation

Evidence

Antimicrobial peptide biology is a real research field. It is also a host-defense peptide with pro-inflammatory activity, and injecting it outside a trial is not a characterized risk.

Evidence Strength

Animal/preclinical only

Caveats

Safety
Alternative Measures
Legal Status

US

Not approved

UK

Not approved

EU

Not approved

AU

Not approved

WADA

Not listed

Not approved. Research chemical.

Citations

No completed peer-reviewed human clinical trial exists for this compound. Where a citation is absent below, that absence is the finding.

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