C

Tier

Kisspeptin-10

Kisspeptin-10

Kisspeptin-10

Upstream reproductive-axis peptide that stimulates GnRH.

Sexual Health

Peptide

WADA Status:

Not listed

Human Trial Scoreboard

Completed human RCTs

0
0
0

Count not verified

Largest Human Study

0
0
0

Size not verified

Longest exposure

0
0
0

Duration not verified

Most Recent Trial

0
0
0

Year not verified

Description

Kisspeptin is a hormone that sits near the top of the reproductive control system, acting on the hypothalamus to trigger the cascade that ultimately produces sex hormones. Kisspeptin-10 is a short active fragment of it, and it has been used mainly as a research tool in human reproductive physiology, notably by the group at Imperial College London. That work is legitimate academic science exploring fertility, puberty and sexual response. It has not become an approved treatment, and no completed randomised controlled trial establishes it as one. Selling a research probe used to map a hormonal pathway as a fertility or libido treatment gets ahead of what the research was ever designed to show.

What Are The Claims

Claims made for this compound: Stimulates the reproductive hormone axis via KISS1R (strong human proof-of-concept); Drives GnRH and LH release; Studied in fertility and reproductive research

Evidence

Real human research exists, but it is mechanistic work on the reproductive axis, not trials of the libido and hormone-optimization uses it is marketed for.

Evidence Strength

Preliminary (human mechanistic studies)

Caveats

Investigational; no marketed product; very short plasma half-life (~4 min).

Safety
Alternative Measures
Legal Status

US

Not approved; investigational

UK

Not approved

EU

Not approved

AU

Not approved

WADA

Not listed

Not approved. Investigational; used in human mechanistic and reproductive-endocrinology research.

Citations

Jayasena et al. (2015). Human Reproduction. Human physiological study. PMID: 26089302. Dhillo et al. (2005). JCEM. PMID: 16174713.

The content on this site is provided for general informational purposes only and is not intended as medical advice, diagnosis, or treatment. Aambrosia sells subscription access to editorial and research content only, no supplement, compound, or other physical product discussed on this site is sold, shipped, or dispensed by Aambrosia. Always consult a qualified healthcare provider before making changes to your diet, supplement routine, or health practices. Aambrosia does not guarantee specific results, and individual outcomes may vary

Culver City California
Support: bio.aambrosia@gmail.com